Nomimicins B–D, new tetronate-class polyketides from a marine-derived actinomycete of the genus Actinomadura

• Zhiwei Zhang,
• Tao Zhou,
• Taehui Yang,
• Keisuke Fukaya,
• Enjuro Harunari,
• Shun Saito,
• Katsuhisa Yamada,
• Chiaki Imada,
• Daisuke Urabe and
• Yasuhiro Igarashi

Beilstein J. Org. Chem. 2021, 17, 2194–2202, doi:10.3762/bjoc.17.141

• ], whereas DSW in other sea areas had not been studied, although a total of 15 DSW pumping stations are operated in Japan. We recently carried out metagenomic analysis of DSW using DGGE and pyrosequencing techniques and revealed that the bacterial community structure in DSW was varied depending on the

A new glance at the chemosphere of macroalgal–bacterial interactions: In situ profiling of metabolites in symbiosis by mass spectrometry

• Marine Vallet,
• Filip Kaftan,
• Veit Grabe,
• Fatemeh Ghaderiardakani,
• Simona Fenizia,
• Aleš Svatoš,
• Georg Pohnert and
• Thomas Wichard

Beilstein J. Org. Chem. 2021, 17, 1313–1322, doi:10.3762/bjoc.17.91

• understanding the macroalgal–bacterial interactions. The chemosphere was proposed as a region that supports chemical mediator-based cross-kingdom interactions [3]. High-throughput sequencing analysis provides the abundance and composition of the bacterial community on macroalgal surfaces [5][6]. It does not

Secondary metabolites of Bacillus subtilis impact the assembly of soil-derived semisynthetic bacterial communities

• Heiko T. Kiesewalter,
• Carlos N. Lozano-Andrade,
• Mikael L. Strube and
• Ákos T. Kovács

Beilstein J. Org. Chem. 2020, 16, 2983–2998, doi:10.3762/bjoc.16.248

• to understand their ecological role. Keywords: Bacillus subtilis; bacterial community; chemical ecology; Lysinibacillus fusiformis; nonribosomal peptides; surfactin; Introduction In nature, bacteria live in complex communities where they interact with various other microorganisms. Most microbial

• , with a defined composition but fewer members [19][21]. Lebeis et al. used an artificial community of 38 bacterial strains to demonstrate that plant phytohormones sculpt the root microbiome [19]. In comparison, Niu et al. established a seven-species bacterial community based on host selection to mimic

• corresponding NRP-deficient strain sfp, or the single-NRP mutants srfAC, ∆ppsC, and ∆pksL, respectively, incapable of producing either surfactin, plipastatin, or bacillaene, and kept the untreated culture as a control (Figure 2). To investigate the impact of B. subtilis NRPs on the bacterial community

Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections

• Matthew B. Calvert,
• Varsha R. Jumde and
• Alexander Titz

Beilstein J. Org. Chem. 2018, 14, 2607–2617, doi:10.3762/bjoc.14.239

• autoinducer-2 is used by both Gram-positive and Gram-negative species. Because highly structurally similar or even identical molecules are employed for bacterial signaling, it is obvious that bacteria also communicate between species, which can be of use for the bacterial community in co-infections. Often

Algicidal lactones from the marine Roseobacter clade bacterium Ruegeria pomeroyi

• Ramona Riclea,
• Julia Gleitzmann,
• Hilke Bruns,
• Corina Junker,
• Barbara Schulz and
• Jeroen S. Dickschat

Beilstein J. Org. Chem. 2012, 8, 941–950, doi:10.3762/bjoc.8.106

• satellites from space [8], sometimes covering large areas of >105 km2 and containing more than 106 cells mL−1. During these blooms bacteria from the Roseobacter clade have been observed as the predominant prokaryotic species accounting for more than half of the total bacterial community [3][4]. DMSP is also